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Ask a Rev Cycle Expert: Therapeutic Apheresis?


Can you please provide a basic description of the difference between CPT® codes 36514 and 36516?


Current Procedural Terminology (CPT®) code 36514 Therapeutic apheresis; for plasma pheresis and CPT® code 36516 Therapeutic apheresis; with extracorporeal immunoadsorption, selective adsorption or selective filtration and plasma reinfusion are both procedures where the patient’s blood is processed in a special piece of equipment that separates and removes one or more blood components, then returns the blood back to the patient’s circulatory system. For CPT® code 36516, the component removed is low density lipoprotein (LDL), and the procedure can take several hours to complete. CPT® code 36514 is the removal of plasma which is then reintroduced to the patient, and is usually used to treat thrombotic thrombocytopenic purpura (TTP) or other microangiopathic hemolytic anemias.

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